Department of Anesthesiology
Author Title [ Type(Asc)] Year
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Journal Article
Hoppa MB, Lana B, Margas W, Dolphin AC, Ryan TA.  2012.  α2δ expression sets presynaptic calcium channel abundance and release probability.. Nature. 486(7401):122-5.
Moskowitz HS, Heuser J, McGraw TE, Ryan TA.  2003.  Targeted chemical disruption of clathrin function in living cells.. Mol Biol Cell. 14(11):4437-47.
Mitchell SJ, Ryan TA.  2004.  Syntaxin-1A is excluded from recycling synaptic vesicles at nerve terminals.. J Neurosci. 24(20):4884-8.
Fernandez-Alfonso T, Kwan R, Ryan TA.  2006.  Synaptic vesicles interchange their membrane proteins with a large surface reservoir during recycling.. Neuron. 51(2):179-86.
Kim SHyun, Ryan TA.  2009.  Synaptic vesicle recycling at CNS snapses without AP-2.. J Neurosci. 29(12):3865-74.
Chi P, Greengard P, Ryan TA.  2003.  Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies.. Neuron. 38(1):69-78.
Ryan TA.  2006.  A pre-synaptic to-do list for coupling exocytosis to endocytosis.. Curr Opin Cell Biol. 18(4):416-21.
Ariel P, Ryan TA.  2012.  New insights into molecular players involved in neurotransmitter release.. Physiology (Bethesda). 27(1):15-24.
Mitchell SJ, Ryan TA.  2005.  Munc18-dependent regulation of synaptic vesicle exocytosis by syntaxin-1A in hippocampal neurons.. Neuropharmacology. 48(3):372-80.
Dittman J, Ryan TA.  2009.  Molecular circuitry of endocytosis at nerve terminals.. Annu Rev Cell Dev Biol. 25:133-60.
Ryan TA.  2003.  Kiss-and-run, fuse-pinch-and-linger, fuse-and-collapse: the life and times of a neurosecretory granule.. Proc Natl Acad Sci U S A. 100(5):2171-3.
Atluri PP, Ryan TA.  2006.  The kinetics of synaptic vesicle reacidification at hippocampal nerve terminals.. J Neurosci. 26(8):2313-20.
Fernandez-Alfonso T, Ryan TA.  2004.  The kinetics of synaptic vesicle pool depletion at CNS synaptic terminals.. Neuron. 41(6):943-53.
Nicholson-Tomishima K, Ryan TA.  2004.  Kinetic efficiency of endocytosis at mammalian CNS synapses requires synaptotagmin I.. Proc Natl Acad Sci U S A. 101(47):16648-52.
Baumgart JP, Zhou Z-Y, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC.  2015.  Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling.. Proc Natl Acad Sci U S A. 112(38):11959-64.
Moskowitz HS, Yokoyama CT, Ryan TA.  2005.  Highly cooperative control of endocytosis by clathrin.. Mol Biol Cell. 16(4):1769-76.
Fernandez-Alfonso T, Ryan TA.  2008.  A heterogeneous "resting" pool of synaptic vesicles that is dynamically interchanged across boutons in mammalian CNS synapses.. Brain Cell Biol. 36(1-4):87-100.
Hemmings HC, Yan W, Westphalen RI, Ryan TA.  2005.  The general anesthetic isoflurane depresses synaptic vesicle exocytosis.. Mol Pharmacol. 67(5):1591-9.
Fernandez-Alfonso T, Ryan TA.  2006.  The efficiency of the synaptic vesicle cycle at central nervous system synapses.. Trends Cell Biol. 16(8):413-20.
Mani M, Lee SYoon, Lucast L, Cremona O, Di Paolo G, De Camilli P, Ryan TA.  2007.  The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals.. Neuron. 56(6):1004-18.
Kim SHyun, Ryan TA.  2009.  A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis.. J Biol Chem. 284(47):32803-12.
Hoppa MB, Gouzer G, Armbruster M, Ryan TA.  2014.  Control and plasticity of the presynaptic action potential waveform at small CNS nerve terminals.. Neuron. 84(4):778-89.
Kim SHyun, Ryan TA.  2010.  CDK5 serves as a major control point in neurotransmitter release.. Neuron. 67(5):797-809.
Balaji J, Armbruster M, Ryan TA.  2008.  Calcium control of endocytic capacity at a CNS synapse.. J Neurosci. 28(26):6742-9.
Pan P-Y, Ryan TA.  2012.  Calbindin controls release probability in ventral tegmental area dopamine neurons.. Nat Neurosci. 15(6):813-5.