Publications | Department of Anesthesiology

Department of Anesthesiology

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Hemmings HC, Nairn AC, Elliott JI, Greengard P. 1990. Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity.. J Biol Chem. 265(33):20369-76.

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McAvoy T, Allen PB, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn AC, Hemmings HC. 1999. Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation.. Biochemistry. 38(39):12943-9.

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Nairn AC, Hemmings HC, Greengard P. 1985. Protein kinases in the brain.. Annu Rev Biochem. 54:931-76.

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Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P. 1995. Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons.. Neuron. 14(2):385-97.

King MM, Huang CY, Chock PB, Nairn AC, Hemmings HC, Chan KF, Greengard P. 1984. Mammalian brain phosphoproteins as substrates for calcineurin.. J Biol Chem. 259(13):8080-3.

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Strålfors P, Hemmings HC, Greengard P. 1989. Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.. Eur J Biochem. 180(1):143-8.

Ratnakumari L, Hemmings HC. 1998. Inhibition of presynaptic sodium channels by halothane.. Anesthesiology. 88(4):1043-54.

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Hemmings HC. 1998. General anesthetic effects on protein kinase C.. Toxicol Lett. 100-101:89-95.

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Hemmings HC, Adamo AI. 1994. Effects of halothane and propofol on purified brain protein kinase C activation.. Anesthesiology. 81(1):147-55.

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Hemmings HC, Girault JA, Nairn AC, Bertuzzi G, Greengard P. 1992. Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.. J Neurochem. 59(3):1053-61.

Absil P, Foidart A, Hemmings HC, Steinbusch HW, Ball GF, Balthazart J. 2001. Distribution of DARPP-32 immunoreactive structures in the quail brain: anatomical relationship with dopamine and aromatase.. J Chem Neuroanat. 21(1):23-39.

Foster GA, Schultzberg M, Hökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P. 1987. Development of a dopamine- and cyclic adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation.. J Neurosci. 7(7):1994-2018.

Hökfelt T, Foster G, Schultzberg M, Meister B, Schalling M, Goldstein M, Hemmings HC, Ouimet C, Greengard P. 1988. DARPP-32 as a marker for D-1 dopaminoceptive cells in the rat brain: prenatal development and presence in glial elements (tanycytes) in the basal hypothalamus.. Adv Exp Med Biol. 235:65-82.

Ouimet CC, Miller PE, Hemmings HC, Walaas SI, Greengard P. 1984. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization.. J Neurosci. 4(1):111-24.

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Girault JA, Hemmings HC, Zorn SH, Gustafson EL, Greengard P. 1990. Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.. J Neurochem. 55(5):1772-83.

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Hemmings HC, Adamo AI, Hoffman MM. 1995. Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C.. Anesth Analg. 81(6):1216-22.

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Hemmings HC, Greengard P. 1989. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus.. J Neurosci. 9(3):851-64.

Williams KR, Hemmings HC, LoPresti MB, Greengard P. 1989. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus.. J Neurosci. 9(10):3631-7.

Ouimet CC, Hemmings HC, Greengard P. 1989. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain.. J Neurosci. 9(3):865-75.

Hudson AE, Hemmings HC. 2011. Are anaesthetics toxic to the brain? Br J Anaesth. 107(1):30-7.

Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW et al.. 2013. Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar.. Br J Anaesth. 111(2):143-51.