Department of Anesthesiology

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Author Title [ Type(Desc)] Year
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Journal Article
Hemmings HC, Adamo AI.  1996.  Activation of endogenous protein kinase C by halothane in synaptosomes.. Anesthesiology. 84(3):652-62.
Girault JA, Walaas SI, Hemmings HC, Greengard P.  1990.  ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain.. Neuroscience. 37(2):317-25.
Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P.  1989.  ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro.. J Biol Chem. 264(13):7726-33.
Hemmings HC, Adamo AI, Hoffman MM.  1995.  Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C.. Anesth Analg. 81(6):1216-22.
Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2006.  D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex.. Behav Brain Res. 171(1):127-33.
Hemmings HC, Nairn AC, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1.. J Biol Chem. 259(23):14491-7.
Hemmings HC, Nairn AC, Aswad DW, Greengard P.  1984.  DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus.. J Neurosci. 4(1):99-110.
Williams KR, Hemmings HC, LoPresti MB, Konigsberg WH, Greengard P.  1986.  DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.. J Biol Chem. 261(4):1890-903.
Nairn AC, Hemmings HC, Walaas SI, Greengard P.  1988.  DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons.. J Neurochem. 50(1):257-62.
Ouimet CC, Hemmings HC, Greengard P.  1988.  Dopamine-regulated protein phosphorylation in the basal ganglia.. Adv Exp Med Biol. 235:1-17.
Caporaso GL, Bibb JA, Snyder GL, Valle C, Rakhilin S, Fienberg AA, Hemmings HC, Nairn AC, Greengard P.  2000.  Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia.. Neuropharmacology. 39(9):1637-44.
Hemmings HC, Adamo AI.  1994.  Effects of halothane and propofol on purified brain protein kinase C activation.. Anesthesiology. 81(1):147-55.
Mayerhofer A, Hemmings HC, Snyder GL, Greengard P, Boddien S, Berg U, Brucker C.  1999.  Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro.. J Clin Endocrinol Metab. 84(1):257-64.
Snyder GL, Galdi S, Hendrick JP, Hemmings HC.  2007.  General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.. Neuropharmacology. 53(5):619-30.
Ward CP, Redd K, Williams BM, Caler JR, Luo Y, McCoy JG.  2002.  Ginkgo biloba extract: cognitive enhancer or antistress buffer.. Pharmacol Biochem Behav. 72(4):913-22.
Ahmed ST, Ivashkiv LB.  2000.  Inhibition of IL-6 and IL-10 signaling and Stat activation by inflammatory and stress pathways.. J Immunol. 165(9):5227-37.
Strålfors P, Hemmings HC, Greengard P.  1989.  Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical.. Eur J Biochem. 180(1):143-8.
Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ.  2001.  Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals.. J Neurosci. 21(20):7944-53.
Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P.  1991.  Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells.. Proc Natl Acad Sci U S A. 88(7):2798-801.
Hotte M, Thuault S, Dineley KT, Hemmings HC, Nairn AC, Jay TM.  2007.  Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo.. Synapse. 61(1):24-8.
Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P.  1989.  Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II.. J Biol Chem. 264(36):21748-59.
Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ et al..  1999.  Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.. Nature. 402(6762):669-71.
Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC.  2005.  Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).. Proc Natl Acad Sci U S A. 102(9):3489-94.
Kanda VA, Purtell K, Abbott GW.  2011.  Protein kinase C downregulates I(Ks) by stimulating KCNQ1-KCNE1 potassium channel endocytosis.. Heart Rhythm. 8(10):1641-7.
Hemmings HC, Nairn AC, Greengard P.  1986.  Protein kinases and phosphoproteins in the nervous system.. Res Publ Assoc Res Nerv Ment Dis. 64:47-69.