Department of Anesthesiology
Author Title Type [ Year(Desc)]
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1999
Moss BL, Silberberg SD, Nimigean CM, Magleby KL.  1999.  Ca2+-dependent gating mechanisms for dSlo, a large-conductance Ca2+-activated K+ (BK) channel.. Biophys J. 76(6):3099-117.
2003
Accardi A, Pusch M.  2003.  Conformational changes in the pore of CLC-0.. J Gen Physiol. 122(3):277-93.
Estévez R, Schroeder BC, Accardi A, Jentsch TJ, Pusch M.  2003.  Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.. Neuron. 38(1):47-59.
Nimigean CM, Chappie JS, Miller C.  2003.  Electrostatic tuning of ion conductance in potassium channels.. Biochemistry. 42(31):9263-8.
Liantonio A, De Luca A, Pierno S, Didonna MPaola, Loiodice F, Fracchiolla G, Tortorella P, Antonio L, Bonerba E, Traverso S et al..  2003.  Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.. Br J Pharmacol. 139(7):1255-64.
2005
Picollo A, Pusch M.  2005.  Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.. Nature. 436(7049):420-3.
Cacheaux LP, Topf N, Tibbs GR, Schaefer UR, Levi R, Harrison NL, Abbott GW, Goldstein PA.  2005.  Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.. J Pharmacol Exp Ther. 315(2):517-25.
2007
Liantonio A, Giannuzzi V, Picollo A, Babini E, Pusch M, D Camerino C.  2007.  Niflumic acid inhibits chloride conductance of rat skeletal muscle by directly inhibiting the CLC-1 channel and by increasing intracellular calcium.. Br J Pharmacol. 150(2):235-47.
2010
Zifarelli G, Liantonio A, Gradogna A, Picollo A, Gramegna G, De Bellis M, Murgia AR, Babini E, D Camerino C, Pusch M.  2010.  Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.. Br J Pharmacol. 160(7):1652-61.
2013
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
2014
Lyashchenko AK, Redd KJ, Goldstein PA, Tibbs GR.  2014.  cAMP control of HCN2 channel Mg2+ block reveals loose coupling between the cyclic nucleotide-gating ring and the pore.. PLoS One. 9(7):e101236.
Lolicato M, Riegelhaupt PM, Arrigoni C, Clark KA, Minor DL.  2014.  Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.. Neuron. 84(6):1198-212.
2017
Menny A, Lefebvre SN, Schmidpeter PAm, Drège E, Fourati Z, Delarue M, Edelstein SJ, Nimigean CM, Joseph D, Corringer P-J.  2017.  Identification of a pre-active conformation of a pentameric channel receptor.. Elife. 6