Department of Anesthesiology
Author Title Type [ Year(Desc)]
Filters: Keyword is Potassium Channels  [Clear All Filters]
1999
Nimigean CM, Magleby KL.  1999.  The beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting states.. J Gen Physiol. 113(3):425-40.
Moss BL, Silberberg SD, Nimigean CM, Magleby KL.  1999.  Ca2+-dependent gating mechanisms for dSlo, a large-conductance Ca2+-activated K+ (BK) channel.. Biophys J. 76(6):3099-117.
2000
Nimigean CM, Magleby KL.  2000.  Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism.. J Gen Physiol. 115(6):719-36.
2002
Nimigean CM, Miller C.  2002.  Na+ block and permeation in a K+ channel of known structure.. J Gen Physiol. 120(3):323-35.
Qian X, Nimigean CM, Niu X, Moss BL, Magleby KL.  2002.  Slo1 tail domains, but not the Ca2+ bowl, are required for the beta 1 subunit to increase the apparent Ca2+ sensitivity of BK channels.. J Gen Physiol. 120(6):829-43.
2003
Sokolova O, Accardi A, Gutierrez D, Lau A, Rigney M, Grigorieff N.  2003.  Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.. Proc Natl Acad Sci U S A. 100(22):12607-12.
Lingamaneni R, Hemmings HC.  2003.  Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na+ channels, Ca2+ channels, and GABA(A) receptors.. Br J Anaesth. 90(2):199-211.
Nimigean CM, Chappie JS, Miller C.  2003.  Electrostatic tuning of ion conductance in potassium channels.. Biochemistry. 42(31):9263-8.
2004
Nimigean CM, Shane T, Miller C.  2004.  A cyclic nucleotide modulated prokaryotic K+ channel.. J Gen Physiol. 124(3):203-10.
2005
Ouyang W, Hemmings HC.  2005.  Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.. J Pharmacol Exp Ther. 312(2):801-8.
Cacheaux LP, Topf N, Tibbs GR, Schaefer UR, Levi R, Harrison NL, Abbott GW, Goldstein PA.  2005.  Impairment of hyperpolarization-activated, cyclic nucleotide-gated channel function by the intravenous general anesthetic propofol.. J Pharmacol Exp Ther. 315(2):517-25.
2006
Zadek B, Nimigean CM.  2006.  Calcium-dependent gating of MthK, a prokaryotic potassium channel.. J Gen Physiol. 127(6):673-85.
2007
Chiu P-L, Pagel MD, Evans J, Chou H-T, Zeng X, Gipson B, Stahlberg H, Nimigean CM.  2007.  The structure of the prokaryotic cyclic nucleotide-modulated potassium channel MloK1 at 16 A resolution.. Structure. 15(9):1053-64.
2008
Thompson AN, Posson DJ, Parsa PV, Nimigean CM.  2008.  Molecular mechanism of pH sensing in KcsA potassium channels.. Proc Natl Acad Sci U S A. 105(19):6900-5.
2009
Thompson AN, Kim I, Panosian TD, Iverson TM, Allen TW, Nimigean CM.  2009.  Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore.. Nat Struct Mol Biol. 16(12):1317-24.
2011
Cheng WWL, McCoy JG, Thompson AN, Nichols CG, Nimigean CM.  2011.  Mechanism for selectivity-inactivation coupling in KcsA potassium channels.. Proc Natl Acad Sci U S A. 108(13):5272-7.
Banerjee S, Nimigean CM.  2011.  Non-vesicular transfer of membrane proteins from nanoparticles to lipid bilayers.. J Gen Physiol. 137(2):217-23.
Nimigean CM, Allen TW.  2011.  Origins of ion selectivity in potassium channels from the perspective of channel block.. J Gen Physiol. 137(5):405-13.
2012
McCoy JG, Nimigean CM.  2012.  Structural correlates of selectivity and inactivation in potassium channels.. Biochim Biophys Acta. 1818(2):272-85.
Ying S-W, Kanda VA, Hu Z, Purtell K, King EC, Abbott GW, Goldstein PA.  2012.  Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.. PLoS One. 7(8):e42756.
2013
Tibbs GR, Rowley TJ, R Sanford L, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD.  2013.  HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain.. J Pharmacol Exp Ther. 345(3):363-73.
2014
Hoppa MB, Gouzer G, Armbruster M, Ryan TA.  2014.  Control and plasticity of the presynaptic action potential waveform at small CNS nerve terminals.. Neuron. 84(4):778-89.
McCoy JG, Rusinova R, Kim DM, Kowal J, Banerjee S, Cartagena AJaramillo, Thompson AN, Kolmakova-Partensky L, Stahlberg H, Andersen OS et al..  2014.  A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics.. J Biol Chem. 289(14):9535-46.
Kowal J, Chami M, Baumgartner P, Arheit M, Chiu P-L, Rangl M, Scheuring S, Schröder GF, Nimigean CM, Stahlberg H.  2014.  Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.. Nat Commun. 5:3106.
Rusinova R, Kim DM, Nimigean CM, Andersen OS.  2014.  Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.. Biophys J. 106(5):1070-8.