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Department of Anesthesiology Bookshelf
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Ion Channel Gating
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Zifarelli G
,
Liantonio A
,
Gradogna A
,
Picollo A
,
Gramegna G
,
De Bellis M
,
Murgia AR
,
Babini E
,
D Camerino C
,
Pusch M
. 2010.
Identification of sites responsible for the potentiating effect of niflumic acid on ClC-Ka kidney chloride channels.
.
Br J Pharmacol. 160(7):1652-61.
PubMed
Google Scholar
Zadek B
,
Nimigean CM
. 2006.
Calcium-dependent gating of MthK, a prokaryotic potassium channel.
.
J Gen Physiol. 127(6):673-85.
PubMed
Google Scholar
Y
Ying S-W
,
Tibbs GR
,
Picollo A
,
Abbas SY
,
R Sanford L
,
Accardi A
,
Hofmann F
,
Ludwig A
,
Goldstein PA
. 2011.
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.
.
J Neurosci. 31(28):10412-23.
PubMed
Google Scholar
Ying S-W
,
Kanda VA
,
Hu Z
,
Purtell K
,
King EC
,
Abbott GW
,
Goldstein PA
. 2012.
Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.
.
PLoS One. 7(8):e42756.
PubMed
Google Scholar
T
Türkaydin B
,
Schewe M
,
Riel EBarbara
,
Schulz F
,
Biedermann J
,
Baukrowitz T
,
Sun H
. 2024.
Atomistic mechanism of coupling between cytosolic sensor domain and selectivity filter in TREK K2P channels.
.
Nat Commun. 15(1):4628.
PubMed
Google Scholar
Thon O
,
Wang Z
,
Schmidpeter PAM
,
Nimigean CM
. 2024.
PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK.
.
Nat Commun. 15(1):8230.
PubMed
Google Scholar
Thompson AN
,
Posson DJ
,
Parsa PV
,
Nimigean CM
. 2008.
Molecular mechanism of pH sensing in KcsA potassium channels.
.
Proc Natl Acad Sci U S A. 105(19):6900-5.
PubMed
Google Scholar
R
Rusinova R
,
Kim DM
,
Nimigean CM
,
Andersen OS
. 2014.
Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.
.
Biophys J. 106(5):1070-8.
PubMed
Google Scholar
Ratnakumari L
,
Hemmings HC
. 1996.
Inhibition by propofol of [3H]-batrachotoxinin-A 20-alpha-benzoate binding to voltage-dependent sodium channels in rat cortical synaptosomes.
.
Br J Pharmacol. 119(7):1498-504.
PubMed
Google Scholar
Ratnakumari L
,
Vysotskaya TN
,
Duch DS
,
Hemmings HC
. 2000.
Differential effects of anesthetic and nonanesthetic cyclobutanes on neuronal voltage-gated sodium channels.
.
Anesthesiology. 92(2):529-41.
PubMed
Google Scholar
P
Pusch M
,
Zifarelli G
,
Murgia AR
,
Picollo A
,
Babini E
. 2006.
Channel or transporter? The CLC saga continues.
Exp Physiol. 91(1):149-52.
PubMed
Google Scholar
Pusch M
,
Accardi A
,
Liantonio A
,
Guida P
,
Traverso S
,
Camerino DConte
,
Conti F
. 2002.
Mechanisms of block of muscle type CLC chloride channels (Review).
.
Mol Membr Biol. 19(4):285-92.
PubMed
Google Scholar
Posson DJ
,
McCoy JG
,
Nimigean CM
. 2013.
The voltage-dependent gate in MthK potassium channels is located at the selectivity filter.
.
Nat Struct Mol Biol. 20(2):159-66.
PubMed
Google Scholar
Picollo A
,
Malvezzi M
,
Accardi A
. 2010.
Proton block of the CLC-5 Cl-/H+ exchanger.
.
J Gen Physiol. 135(6):653-9.
PubMed
Google Scholar
Panaghie G
,
Purtell K
,
Tai K-K
,
Abbott GW
. 2008.
Voltage-dependent C-type inactivation in a constitutively open K+ channel.
.
Biophys J. 95(6):2759-78.
PubMed
Google Scholar
Pan Y
,
Pohjolainen E
,
Schmidpeter PAM
,
Vaiana AC
,
Nimigean CM
,
Grubmüller H
,
Scheuring S
. 2023.
Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel.
.
Nat Struct Mol Biol. 30(4):512-520.
PubMed
Google Scholar
O
Ouyang W
,
Hemmings HC
. 2007.
Isoform-selective effects of isoflurane on voltage-gated Na+ channels.
.
Anesthesiology. 107(1):91-8.
PubMed
Google Scholar
Ouyang W
,
Hemmings HC
. 2005.
Depression by isoflurane of the action potential and underlying voltage-gated ion currents in isolated rat neurohypophysial nerve terminals.
.
J Pharmacol Exp Ther. 312(2):801-8.
PubMed
Google Scholar
Ouyang W
,
Jih T-Y
,
Zhang T-T
,
Correa AM
,
Hemmings HC
. 2007.
Isoflurane inhibits NaChBac, a prokaryotic voltage-gated sodium channel.
.
J Pharmacol Exp Ther. 322(3):1076-83.
PubMed
Google Scholar
N
Nimigean CM
,
Magleby KL
. 1999.
The beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting states.
.
J Gen Physiol. 113(3):425-40.
PubMed
Google Scholar
Nimigean CM
,
Magleby KL
. 2000.
Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism.
.
J Gen Physiol. 115(6):719-36.
PubMed
Google Scholar
Nimigean CM
,
Allen TW
. 2011.
Origins of ion selectivity in potassium channels from the perspective of channel block.
.
J Gen Physiol. 137(5):405-13.
PubMed
Google Scholar
Nimigean CM
,
Miller C
. 2002.
Na+ block and permeation in a K+ channel of known structure.
.
J Gen Physiol. 120(3):323-35.
PubMed
Google Scholar
Nimigean CM
,
Chappie JS
,
Miller C
. 2003.
Electrostatic tuning of ion conductance in potassium channels.
.
Biochemistry. 42(31):9263-8.
PubMed
Google Scholar
Neelsen LC
,
Riel EB
,
Rinné S
,
Schmid F-R
,
Jürs BC
,
Bedoya M
,
Langer JP
,
Eymsh B
,
Kiper AK
,
Cordeiro S
et al.
. 2024.
Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.
.
Nat Commun. 15(1):7545.
PubMed
Google Scholar
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