We are seeing patients in-person and through Video Visits. Learn more about how we’re keeping you safe and please review our updated visitor policy. Please also consider supporting Weill Cornell Medicine’s efforts to support our front-line workers.
Author Title [ Type(Desc)] Year
Filters: Author is Nimigean, Crina M  [Clear All Filters]
Journal Article
Fan C, Sukomon N, Flood E, Rheinberger J, Allen TW, Nimigean CM.  2020.  Ball-and-chain inactivation in a calcium-gated potassium channel.. Nature. 580(7802):288-293.
Posson DJ, Rusinova R, Andersen OS, Nimigean CM.  2015.  Calcium ions open a selectivity filter gate during activation of the MthK potassium channel.. Nat Commun. 6:8342.
Zadek B, Nimigean CM.  2006.  Calcium-dependent gating of MthK, a prokaryotic potassium channel.. J Gen Physiol. 127(6):673-85.
Kim DM, Dikiy I, Upadhyay V, Posson DJ, Eliezer D, Nimigean CM.  2016.  Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles.. J Gen Physiol. 148(2):119-32.
Nimigean CM, Shane T, Miller C.  2004.  A cyclic nucleotide modulated prokaryotic K+ channel.. J Gen Physiol. 124(3):203-10.
Nimigean CM, Chappie JS, Miller C.  2003.  Electrostatic tuning of ion conductance in potassium channels.. Biochemistry. 42(31):9263-8.
Kowal J, Biyani N, Chami M, Scherer S, Rzepiela AJ, Baumgartner P, Upadhyay V, Nimigean CM, Stahlberg H.  2018.  High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.. Structure. 26(1):20-27.e3.
Menny A, Lefebvre SN, Schmidpeter PAm, Drège E, Fourati Z, Delarue M, Edelstein SJ, Nimigean CM, Joseph D, Corringer P-J.  2017.  Identification of a pre-active conformation of a pentameric channel receptor.. Elife. 6
Xu Y, Zhang D, Rogawski R, Nimigean CM, McDermott AE.  2019.  Identifying coupled clusters of allostery participants through chemical shift perturbations.. Proc Natl Acad Sci U S A. 116(6):2078-2085.
McCoy JG, Rusinova R, Kim DM, Kowal J, Banerjee S, Cartagena AJaramillo, Thompson AN, Kolmakova-Partensky L, Stahlberg H, Andersen OS et al..  2014.  A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics.. J Biol Chem. 289(14):9535-46.
Nimigean CM, Pagel MD.  2007.  Ligand binding and activation in a prokaryotic cyclic nucleotide-modulated channel.. J Mol Biol. 371(5):1325-37.
Schmidpeter PAM, Gao X, Uphadyay V, Rheinberger J, Nimigean CM.  2018.  Ligand binding and activation properties of the purified bacterial cyclic nucleotide-gated channel SthK.. J Gen Physiol.
Rheinberger J, Gao X, Schmidpeter PAm, Nimigean CM.  2018.  Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.. Elife. 7
Kowal J, Chami M, Baumgartner P, Arheit M, Chiu P-L, Rangl M, Scheuring S, Schröder GF, Nimigean CM, Stahlberg H.  2014.  Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.. Nat Commun. 5:3106.
Cheng WWL, McCoy JG, Thompson AN, Nichols CG, Nimigean CM.  2011.  Mechanism for selectivity-inactivation coupling in KcsA potassium channels.. Proc Natl Acad Sci U S A. 108(13):5272-7.
Thompson AN, Kim I, Panosian TD, Iverson TM, Allen TW, Nimigean CM.  2009.  Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore.. Nat Struct Mol Biol. 16(12):1317-24.
Posson DJ, Thompson AN, McCoy JG, Nimigean CM.  2013.  Molecular interactions involved in proton-dependent gating in KcsA potassium channels.. J Gen Physiol. 142(6):613-24.
Thompson AN, Posson DJ, Parsa PV, Nimigean CM.  2008.  Molecular mechanism of pH sensing in KcsA potassium channels.. Proc Natl Acad Sci U S A. 105(19):6900-5.
Nimigean CM, Miller C.  2002.  Na+ block and permeation in a K+ channel of known structure.. J Gen Physiol. 120(3):323-35.
Banerjee S, Nimigean CM.  2011.  Non-vesicular transfer of membrane proteins from nanoparticles to lipid bilayers.. J Gen Physiol. 137(2):217-23.
Nimigean CM, Allen TW.  2011.  Origins of ion selectivity in potassium channels from the perspective of channel block.. J Gen Physiol. 137(5):405-13.
Nimigean CM.  2020.  Polyamine block of MthK potassium channels.. J Gen Physiol. 152(7)
Nimigean CM.  2006.  A radioactive uptake assay to measure ion transport across ion channel-containing liposomes.. Nat Protoc. 1(3):1207-12.
Rangl M, Miyagi A, Kowal J, Stahlberg H, Nimigean CM, Scheuring S.  2016.  Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels.. Nat Commun. 7:12789.
Rusinova R, Kim DM, Nimigean CM, Andersen OS.  2014.  Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.. Biophys J. 106(5):1070-8.