Skip to main content
Enter the terms you wish to search for.
Select Search Option
This Site
All WCM Sites
Directory
Menu
Weill Cornell Medicine
Care
Discover
Teach
Department of Anesthesiology
Explore this Website
Home
About Us
Toggle About Us menu options
Mission Statement
Department Leadership
Our Faculty
Contact Us
Career Opportunities
Toggle Career Opportunities menu options
Assistant Professor-NYPQ
Assistant Professor-WCM
Quality and Patient Safety
History
Ways to Give
For Patients
Toggle For Patients menu options
Types of Anesthesia
Pain Management
Billing Questions
Research
Toggle Research menu options
Clinical and Translational Research
Toggle Clinical and Translational Research menu options
Anesthesia Trials Group
Toggle Anesthesia Trials Group menu options
Affiliations
Anesthesia Trials Group Publications
Clinical Trials Directory
Who We Are
Center for Perioperative Outcomes
Human Rights Impact Lab
MADE Lab
Basic Science Research
Annual Research Expo
Publications
Toggle Publications menu options
Department of Anesthesiology Bookshelf
Research Opportunities
Education
Toggle Education menu options
Residency Program
Toggle Residency Program menu options
Education Leadership
Rotations
Curriculum
Van Poznak Research Scholarship
Simulation Education
Residency Program News
Meet the Residents
Toggle Meet the Residents menu options
Class of 2002
Class of 2003
Class of 2004
Class of 2005
Class of 2006
Class of 2007
Class of 2008
Class of 2009
Class of 2010
Class of 2011
Class of 2012
Class of 2013
Class of 2014
Class of 2015
Class of 2016
Class of 2017
Class of 2018
Benefits and Salary
Application FAQs
Chief Residents' Corner
Residency Support Council
Fellowships
Toggle Fellowships menu options
Tri-Institutional Pain Fellowship
Obstetric Anesthesiology Fellowship
Regional Anesthesiology Fellowship
Anesthesiology Critical Care Medicine Fellowship
Global Health Fellowship
Neuroanesthesiology Fellowship
Thoracic Anesthesiology Fellowship
Cardiothoracic Anesthesiology
Study Opportunities for Medical Students
Toggle Study Opportunities for Medical Students menu options
Anesthesiology Diversity Visiting Student Sub-Internship Program
Clinical Anesthesiology Elective
Clinical Cardiovascular Physiology Elective
Grand Rounds
Toggle Grand Rounds menu options
Past Grand Rounds
Future Grand Rounds
Diversity and Inclusion
Extended Reality Anes Immersion Lab (XRAIL)
Toggle Extended Reality Anes Immersion Lab (XRAIL) menu options
Affiliations
Who We Are
XRAIL Publications
XRAIL: In the Media
Global Health Initiative
Toggle Global Health Initiative menu options
Resident Programs
Fellowship Program
Research
Faculty
Make a Gift
General Registration
NS 3090: Global Health Case Studies
Divisions
Toggle Divisions menu options
Ambulatory Surgery
Cardiac Anesthesiology
Critical Care Anesthesiology
Neuroanesthesiology
Obstetric Anesthesiology
Pain Management
Pediatric Anesthesiology
Regional Anesthesiology & Acute Pain Medicine
Thoracic Anesthesiology
News and Highlights
Our People
Toggle Our People menu options
Faculty-WCM/LMH
Faculty-NYPQ
CRNAs
Toggle CRNAs menu options
CRNA-NYP/LMH Roster
CRNA-NYP/WCMC Roster
CRNA NYPQ Roster
Eleanor Bradley Award
Richie Lyons CRNA of the Year Award
Residents
Nurse Practitioners (NPs)
Alumni
Weill Cornell Medicine
Care
Discover
Teach
Home
About Us
For Patients
Research
Education
Divisions
News and Highlights
Our People
Alumni
Home
Publications
Publications
Clinical and Translational Research
Basic Science Research
Annual Research Expo
Publications
Research Opportunities
Explore
Department of Anesthesiology Bookshelf
Author
Title
[
Type
]
Year
Filters:
Author
is
Accardi, Alessio
[Clear All Filters]
Journal Article
Fortea E
,
Lee S
,
Chadda R
,
Argyros Y
,
Sandal P
,
Mahoney-Kruszka R
,
Ciftci HDidar
,
Falzone ME
,
Huysmans G
,
Robertson JL
et al.
. 2024.
Author Correction: Structural basis of pH-dependent activation in a CLC transporter.
.
Nat Struct Mol Biol.
PubMed
Google Scholar
Leisle L
,
Lam K
,
Dehghani-Ghahnaviyeh S
,
Fortea E
,
Galpin JD
,
Ahern CA
,
Tajkhorshid E
,
Accardi A
. 2022.
Backbone amides are determinants of Cl- selectivity in CLC ion channels.
.
Nat Commun. 13(1):7508.
PubMed
Google Scholar
Picollo A
,
Malvezzi M
,
Houtman JCD
,
Accardi A
. 2009.
Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters.
.
Nat Struct Mol Biol. 16(12):1294-301.
PubMed
Google Scholar
Iyer R
,
Iverson TM
,
Accardi A
,
Miller C
. 2002.
A biological role for prokaryotic ClC chloride channels.
.
Nature. 419(6908):715-8.
PubMed
Google Scholar
Malvezzi M
,
Chalat M
,
Janjusevic R
,
Picollo A
,
Terashima H
,
Menon AK
,
Accardi A
. 2013.
Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.
.
Nat Commun. 4:2367.
PubMed
Google Scholar
Accardi A
. 2015.
CELL SIGNALING. Lipids link ion channels and cancer.
.
Science. 349(6250):789-90.
PubMed
Google Scholar
Accardi A
,
Picollo A
. 2010.
CLC channels and transporters: proteins with borderline personalities.
.
Biochim Biophys Acta. 1798(8):1457-64.
PubMed
Google Scholar
Sokolova O
,
Accardi A
,
Gutierrez D
,
Lau A
,
Rigney M
,
Grigorieff N
. 2003.
Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.
.
Proc Natl Acad Sci U S A. 100(22):12607-12.
PubMed
Google Scholar
Accardi A
,
Pusch M
. 2003.
Conformational changes in the pore of CLC-0.
.
J Gen Physiol. 122(3):277-93.
PubMed
Google Scholar
Basilio D
,
Noack K
,
Picollo A
,
Accardi A
. 2014.
Conformational changes required for H(+)/Cl(-) exchange mediated by a CLC transporter.
.
Nat Struct Mol Biol. 21(5):456-63.
PubMed
Google Scholar
Estévez R
,
Schroeder BC
,
Accardi A
,
Jentsch TJ
,
Pusch M
. 2003.
Conservation of chloride channel structure revealed by an inhibitor binding site in ClC-1.
.
Neuron. 38(1):47-59.
PubMed
Google Scholar
Khelashvili G
,
Falzone ME
,
Cheng X
,
Lee B-C
,
Accardi A
,
Weinstein H
. 2019.
Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca-bound nhTMEM16.
.
Nat Commun. 10(1):4972.
PubMed
Google Scholar
Hara Y
,
Balci-Hayta B
,
Yoshida-Moriguchi T
,
Kanagawa M
,
de Bernabé DBeltrán-V
,
Gündeşli H
,
Willer T
,
Satz JS
,
Crawford RW
,
Burden SJ
et al.
. 2011.
A dystroglycan mutation associated with limb-girdle muscular dystrophy.
.
N Engl J Med. 364(10):939-46.
PubMed
Google Scholar
Lee B-C
,
Khelashvili G
,
Falzone M
,
Menon AK
,
Weinstein H
,
Accardi A
. 2018.
Gating mechanism of the extracellular entry to the lipid pathway in a TMEM16 scramblase.
.
Nat Commun. 9(1):3251.
PubMed
Google Scholar
Feng Z
,
Di Zanni E
,
Alvarenga O
,
Chakraborty S
,
Rychlik N
,
Accardi A
. 2024.
In or out of the groove? Mechanisms of lipid scrambling by TMEM16 proteins.
Cell Calcium. 121:102896.
PubMed
Google Scholar
Jayaram H
,
Accardi A
,
Wu F
,
Williams C
,
Miller C
. 2008.
Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.
.
Proc Natl Acad Sci U S A. 105(32):11194-9.
PubMed
Google Scholar
Accardi A
,
Kolmakova-Partensky L
,
Williams C
,
Miller C
. 2004.
Ionic currents mediated by a prokaryotic homologue of CLC Cl- channels.
.
J Gen Physiol. 123(2):109-19.
PubMed
Google Scholar
Falzone ME
,
Malvezzi M
,
Lee B-C
,
Accardi A
. 2018.
Known structures and unknown mechanisms of TMEM16 scramblases and channels.
.
J Gen Physiol.
PubMed
Google Scholar
Pusch M
,
Accardi A
,
Liantonio A
,
Guida P
,
Traverso S
,
Camerino DConte
,
Conti F
. 2002.
Mechanisms of block of muscle type CLC chloride channels (Review).
.
Mol Membr Biol. 19(4):285-92.
PubMed
Google Scholar
Khelashvili G
,
Cheng X
,
Falzone ME
,
Doktorova M
,
Accardi A
,
Weinstein H
. 2020.
Membrane lipids are both the substrates and a mechanistically responsive environment of TMEM16 scramblase proteins.
.
J Comput Chem. 41(6):538-551.
PubMed
Google Scholar
Liantonio A
,
Accardi A
,
Carbonara G
,
Fracchiolla G
,
Loiodice F
,
Tortorella P
,
Traverso S
,
Guida P
,
Pierno S
,
De Luca A
et al.
. 2002.
Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.
.
Mol Pharmacol. 62(2):265-71.
PubMed
Google Scholar
Lee B-C
,
Menon AK
,
Accardi A
. 2016.
The nhTMEM16 Scramblase Is Also a Nonselective Ion Channel.
.
Biophys J. 111(9):1919-1924.
PubMed
Google Scholar
Corral-Rodríguez MÁngeles
,
Stuiver M
,
Abascal-Palacios G
,
Diercks T
,
Oyenarte I
,
Ereño-Orbea J
,
de Opakua AIbáñez
,
Blanco FJ
,
Encinar JAntonio
,
Spiwok V
et al.
. 2014.
Nucleotide binding triggers a conformational change of the CBS module of the magnesium transporter CNNM2 from a twisted towards a flat structure.
.
Biochem J. 464(1):23-34.
PubMed
Google Scholar
Malvezzi M
,
Andra KK
,
Pandey K
,
Lee B-C
,
Falzone ME
,
Brown A
,
Iqbal R
,
Menon AK
,
Accardi A
. 2018.
Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases.
.
Proc Natl Acad Sci U S A. 115(30):E7033-E7042.
PubMed
Google Scholar
Ying S-W
,
Tibbs GR
,
Picollo A
,
Abbas SY
,
R Sanford L
,
Accardi A
,
Hofmann F
,
Ludwig A
,
Goldstein PA
. 2011.
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons.
.
J Neurosci. 31(28):10412-23.
PubMed
Google Scholar
1
(current)
2
next ›
last »