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Nimigean, Crina M
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Journal Article
Fan C
,
Sukomon N
,
Flood E
,
Rheinberger J
,
Allen TW
,
Nimigean CM
. 2020.
Ball-and-chain inactivation in a calcium-gated potassium channel.
.
Nature. 580(7802):288-293.
PubMed
Google Scholar
Posson DJ
,
Rusinova R
,
Andersen OS
,
Nimigean CM
. 2015.
Calcium ions open a selectivity filter gate during activation of the MthK potassium channel.
.
Nat Commun. 6:8342.
PubMed
Google Scholar
Zadek B
,
Nimigean CM
. 2006.
Calcium-dependent gating of MthK, a prokaryotic potassium channel.
.
J Gen Physiol. 127(6):673-85.
PubMed
Google Scholar
Kim DM
,
Dikiy I
,
Upadhyay V
,
Posson DJ
,
Eliezer D
,
Nimigean CM
. 2016.
Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles.
.
J Gen Physiol. 148(2):119-32.
PubMed
Google Scholar
Nimigean CM
,
Shane T
,
Miller C
. 2004.
A cyclic nucleotide modulated prokaryotic K+ channel.
.
J Gen Physiol. 124(3):203-10.
PubMed
Google Scholar
Nimigean CM
,
Chappie JS
,
Miller C
. 2003.
Electrostatic tuning of ion conductance in potassium channels.
.
Biochemistry. 42(31):9263-8.
PubMed
Google Scholar
Kowal J
,
Biyani N
,
Chami M
,
Scherer S
,
Rzepiela AJ
,
Baumgartner P
,
Upadhyay V
,
Nimigean CM
,
Stahlberg H
. 2018.
High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.
.
Structure. 26(1):20-27.e3.
PubMed
Google Scholar
Menny A
,
Lefebvre SN
,
Schmidpeter PAm
,
Drège E
,
Fourati Z
,
Delarue M
,
Edelstein SJ
,
Nimigean CM
,
Joseph D
,
Corringer P-J
. 2017.
Identification of a pre-active conformation of a pentameric channel receptor.
.
Elife. 6
PubMed
Google Scholar
Xu Y
,
Zhang D
,
Rogawski R
,
Nimigean CM
,
McDermott AE
. 2019.
Identifying coupled clusters of allostery participants through chemical shift perturbations.
.
Proc Natl Acad Sci U S A. 116(6):2078-2085.
PubMed
Google Scholar
McCoy JG
,
Rusinova R
,
Kim DM
,
Kowal J
,
Banerjee S
,
Cartagena AJaramillo
,
Thompson AN
,
Kolmakova-Partensky L
,
Stahlberg H
,
Andersen OS
et al.
. 2014.
A KcsA/MloK1 chimeric ion channel has lipid-dependent ligand-binding energetics.
.
J Biol Chem. 289(14):9535-46.
PubMed
Google Scholar
Nimigean CM
,
Pagel MD
. 2007.
Ligand binding and activation in a prokaryotic cyclic nucleotide-modulated channel.
.
J Mol Biol. 371(5):1325-37.
PubMed
Google Scholar
Schmidpeter PAM
,
Gao X
,
Uphadyay V
,
Rheinberger J
,
Nimigean CM
. 2018.
Ligand binding and activation properties of the purified bacterial cyclic nucleotide-gated channel SthK.
.
J Gen Physiol.
PubMed
Google Scholar
Rheinberger J
,
Gao X
,
Schmidpeter PAm
,
Nimigean CM
. 2018.
Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
.
Elife. 7
PubMed
Google Scholar
Kowal J
,
Chami M
,
Baumgartner P
,
Arheit M
,
Chiu P-L
,
Rangl M
,
Scheuring S
,
Schröder GF
,
Nimigean CM
,
Stahlberg H
. 2014.
Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
.
Nat Commun. 5:3106.
PubMed
Google Scholar
Cheng WWL
,
McCoy JG
,
Thompson AN
,
Nichols CG
,
Nimigean CM
. 2011.
Mechanism for selectivity-inactivation coupling in KcsA potassium channels.
.
Proc Natl Acad Sci U S A. 108(13):5272-7.
PubMed
Google Scholar
Thompson AN
,
Kim I
,
Panosian TD
,
Iverson TM
,
Allen TW
,
Nimigean CM
. 2009.
Mechanism of potassium-channel selectivity revealed by Na(+) and Li(+) binding sites within the KcsA pore.
.
Nat Struct Mol Biol. 16(12):1317-24.
PubMed
Google Scholar
Posson DJ
,
Thompson AN
,
McCoy JG
,
Nimigean CM
. 2013.
Molecular interactions involved in proton-dependent gating in KcsA potassium channels.
.
J Gen Physiol. 142(6):613-24.
PubMed
Google Scholar
Thompson AN
,
Posson DJ
,
Parsa PV
,
Nimigean CM
. 2008.
Molecular mechanism of pH sensing in KcsA potassium channels.
.
Proc Natl Acad Sci U S A. 105(19):6900-5.
PubMed
Google Scholar
Nimigean CM
,
Miller C
. 2002.
Na+ block and permeation in a K+ channel of known structure.
.
J Gen Physiol. 120(3):323-35.
PubMed
Google Scholar
Banerjee S
,
Nimigean CM
. 2011.
Non-vesicular transfer of membrane proteins from nanoparticles to lipid bilayers.
.
J Gen Physiol. 137(2):217-23.
PubMed
Google Scholar
Nimigean CM
,
Allen TW
. 2011.
Origins of ion selectivity in potassium channels from the perspective of channel block.
.
J Gen Physiol. 137(5):405-13.
PubMed
Google Scholar
Nimigean CM
. 2020.
Polyamine block of MthK potassium channels.
.
J Gen Physiol. 152(7)
PubMed
Google Scholar
Nimigean CM
. 2006.
A radioactive uptake assay to measure ion transport across ion channel-containing liposomes.
.
Nat Protoc. 1(3):1207-12.
PubMed
Google Scholar
Rangl M
,
Miyagi A
,
Kowal J
,
Stahlberg H
,
Nimigean CM
,
Scheuring S
. 2016.
Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels.
.
Nat Commun. 7:12789.
PubMed
Google Scholar
Rusinova R
,
Kim DM
,
Nimigean CM
,
Andersen OS
. 2014.
Regulation of ion channel function by the host lipid bilayer examined by a stopped-flow spectrofluorometric assay.
.
Biophys J. 106(5):1070-8.
PubMed
Google Scholar
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